Gene Expression services

NIZO food research has more than 20 years of experience in the application of genetic engineering in lactic acid bacteria (LAB) and especially Lactococcus lactis. Genetic engineering has been used to analyze and optimize the properties of a wide variety of LAB and for the construction of strains that produce bacterial and eukaryotic proteins, polysaccharides or various metabolites.
Next to L. lactis, extensive expertise is present for Lactobacillus plantarum, Lb. delbrueckii subsp. Bulgaricus, Lb. reuteri, Streptococcus thermophilus, Leuconostoc mesenteroides and Bacillus subtilis.

From this experience NIZO food research offers two Services:

1. Contract research projects in all areas of gene expression and genomics of LAB
 - The NICE system – NIsin Controlled gene Expression in Lactococcus lactis
 - Expression of membrane proteins in L. lactis
 - 3000-L-scale expression and purification of lysostaphin using the NICE system 
 - genomics, arrays etc.

2. Distribution of strains and vectors for gene expression in Lactococcus lactis, other LAB and in Bacillus subtilis
 - Lactococcus lactis
 - Lactobacillus plantarum and other LAB
 - Bacillus subtilis